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Ari Akerstein

Ari Akerstein

I build tools for people who don't have time to waste.

Started as a scientist — molecular biology at UCSF, cancer research. Realized early that tools have more leverage than publications. Made the jump to tech. Fifteen years later: Facebook, Walmart Labs, J&J. Products used by billions. More than a few spectacular failures. Both teach you something.

Then in 2018, I was the patient. New dad, cancer diagnosis. The system gave me data. What I needed was a framework.

So I built one. Probability trees. Second opinions. I PM'd my own treatment. That framework probably saved my life — and it made healthcare permanently personal.

Now I run Cancer Hacker Lab, a healthtech accelerator, and build Navis Health — AI-powered second opinions for cancer patients who don't know how to fight back yet.

Why axestack?

Working with founders, I kept seeing the same stuck pattern: smart people, good ideas, no signal. Not because the ideas were bad — because validation was too slow, pitches were too muddy, and the tools were scattered across a dozen apps that didn't talk to each other.

Axestack is the stack I use — mostly Claude skills. Think of it as a compressed knowledge base and best practices to get things done. An AI toolbelt for founders.

What I Believe

  • Speed is the corrective. Reality fixes self-delusion faster than any advice.
  • Earn your dopamine. The things that matter come from real immersion, not shortcuts.
  • Bloat is a symptom. You can always tell when software was built by committee.
  • Pull over push. Build things you'd build even if you didn't need the money.
  • Don't smooth the spikes. Differences are the edge — nurture them.
  • Physics is the only real limit. Everything else is a constraint you can redesign.

Operating Systems

I organize everything I build into systems by domain.

Patient OS

Tools for patients who fight.

Vitality OS · Family OS

Health, longevity, and family systems. Coming soon.

Field Notes

Writing on building, health, and life experiments →

Let's build something.